Morphine and related drugs: SAR of Morphine analogues, Morphine sulphate, Codeine, Meperidine hydrochloride, Anilerdine hydrochloride, Diphenoxylate hydrochloride, Loperamide hydrochloride, Fentanyl citrate*, Methadone hydrochloride*, Propoxyphene hydrochloride, Pentazocine, Levorphanol tartarate. Ultra short acting barbitutrates: Methohexital sodium*, Thiamylal sodium, Thiopental sodium.ĭissociative anesthetics: Ketamine hydrochloride.*
Inhalation anesthetics: Halothane*, Methoxyflurane, Enflurane, Sevoflurane, Isoflurane, Desflurane.
Miscellaneous: Primidone, Valproic acid, Gabapentin, Felbamate Urea and monoacylureas: Phenacemide, Carbamazepine* Succinimides: Phensuximide, Methsuximide, Ethosuximide* Oxazolidine diones: Trimethadione, Paramethadione Hydantoins: Phenytoin*, Mephenytoin, Ethotoin Anticonvulsants: SAR of Anticonvulsants, mechanism of anticonvulsant actionīarbiturates: Phenobarbitone, Methabarbital. Ring Analogues of Phenothiazeines: Chlorprothixene, Thiothixene, Loxapine succinate, Clozapine.įluro buterophenones: Haloperidol, Droperidol, Risperidone.īeta amino ketones: Molindone hydrochloride.Ĭ. Phenothiazeines: SAR of Phenothiazeines – Promazine hydrochloride, Chlorpromazine hydrochloride*, Triflupromazine, Thioridazine hydrochloride, Piperacetazine hydrochloride, Prochlorperazine maleate, Trifluoperazine hydrochloride. Sedatives and Hypnotics:Benzodiazepines: SAR of Benzodiazepines, Chlordiazepoxide, Diazepam*, Oxazepam, Chlorazepate, Lorazepam, Alprazolam, Zolpidemīarbiturtes: SAR of barbiturates, Barbital*, Phenobarbital, Mephobarbital, Amobarbital, Butabarbital, Pentobarbital, SecobarbitalĪlcohol & their carbamate derivatives: Meprobomate, Ethchlorvynol.Īldehyde & their derivatives: Triclofos sodium, Paraldehyde. Synthetic cholinergic blocking agents: Tropicamide, Cyclopentolate hydrochloride, Clidinium bromide, Dicyclomine hydrochloride*, Glycopyrrolate, Methantheline bromide, Propantheline bromide, Benztropine mesylate, Orphenadrine citrate, Biperidine hydrochloride, Procyclidine hydrochloride*, Tridihexethyl chloride, Isopropamide iodide, Ethopropazine hydrochloride.Ī. Solanaceous alkaloids and analogues: Atropine sulphate, Hyoscyamine sulphate, Scopolamine hydrobromide, Homatropine hydrobromide, Ipratropium bromide*. Physostigmine, Neostigmine*, Pyridostigmine, Edrophonium chloride, Tacrine hydrochloride, Ambenonium chloride, Isofluorphate, Echothiophate iodide, Parathione, Malathion.Ĭholinesterase reactivator: Pralidoxime chloride.Ĭholinergic Blocking agents: SAR of cholinolytic agents Indirect acting/ Cholinesterase inhibitors (Reversible & Irreversible): Parasympathomimetic agents: SAR of Parasympathomimetic agentsĭirect acting agents: Acetylcholine, Carbachol*, Bethanechol, Methacholine, Pilocarpine. Agents with mixed mechanism: Ephedrine, Metaraminol.Īlpha adrenergic blockers: Tolazoline*, Phentolamine, Phenoxybenzamine, Prazosin, Dihydroergotamine, Methysergide.īeta adrenergic blockers: SAR of beta blockers, Propranolol*, Metibranolol, Atenolol, Betazolol, Bisoprolol, Esmolol, Metoprolol, Labetolol, Carvedilol.īiosynthesis and catabolism of acetylcholine.Cholinergic receptors (Muscarinic & Nicotinic) and their distribution.Indirect acting agents: Hydroxyamphetamine, Pseudoephedrine, Propylhexedrine.Methyldopa, Clonidine, Dobutamine, Isoproterenol, Terbutaline, Salbutamol*, Bitolterol, Naphazoline, Oxymetazoline and Xylometazoline. Sympathomimetic agents: SAR of Sympathomimetic agentsĭirect acting: Norepinephrine, Epinephrine, Phenylephrine*, Dopamine, Ionization, Solubility, Partition Coefficient, Hydrogen bonding, Protein binding, Chelation, Bioisosterism, Optical and Geometrical isomerism.ĭrug metabolism principles- Phase I and Phase II.Factors affecting drug metabolism including stereo chemical aspects.Īdrenergic Neurotransmitters:Biosynthesis and catabolism of catecholamine.Īdrenergic receptors (Alpha & Beta) and their distribution.
History and development of medicinal chemistry Physicochemical properties in relation to biological action Name of the Subject: MEDICINAL CHEMISTRY – I (Theory)
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